A Useful Modification of the Prothrombin Time.
نویسندگان
چکیده
medical profession with a very useful tool. This test is widely used today for control of anticoagulant therapy, as a preoperative test of hemostatic function, and as a liver function test, both in geriatric and pediatric practice. However, the methodology of the usual procedure either excludes or limits its employment for certain types of patients: the patient with poor or thronibosed VC1flS, tile apprehensive acute cardiac on anticoagulant treatmnent who becomes agitated upon venipuncture, tile pediatric patient requiring repeated determinations, and others. This has given impetus for devising a modification of the prothrornbin test which would have the advantages of being simple, dependable, universally applicable, and of supplying the physician with results in a short time, even in a large hospital service. It is the purpose of this paper to describe a modification of the prothrombin test which has beeii found applicable to every type of patient, employs a nhinimum amount of blood, and allows an accurate result to be recorded within 3-4 miii. after obtaining the specimen.
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A modification is described which reduces considerably the amount of pipetting involved in the estimation of "prothrombin time."The procedure used by the authors is described in full. Particular attention is paid to the preparation and storage of the thromboplastin and to the sterilization of the citrate tubes used for the collection of specimens.
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عنوان ژورنال:
- Clinical chemistry
دوره 10 شماره
صفحات -
تاریخ انتشار 1964